Publications　研究成果｜東京医科大学分子病理学分野

Kuroda - Laboratory

Publications

研究成果

2024 / R6 2023 / R5 2022 / R4 2021 / R3 2020 / R2 2019 / R1 2018 / H30 2017 / H29 2016 / H28 2015 / H27 2014 / H26 2013 / H25 2012 / H24 2011 / H23 2010 / H22 2009 / H21 ~2008 / ~H20

2024 / R6

Susumu Takeuchi, Akinobu Yoshimura, Atsushi Sofuni, Yuri Ueda, Tomohiro Umezu, Masahiko Kuroda, Aoi Sukeda, Jun Matsubayashi, Toshitaka Nagao, Masato Bingo, Natsuko Inagaki, Tatsuo Ohira, Masahiro Seike, Norihiko Ikeda.
A single-institution retrospective study of comprehensive genomic profiling tests based on C-CAT findings for advanced solid cancers.
Jpn J Clin Oncol. 2024 Sep 19:hyae128. doi: 10.1093/jjco/hyae128. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/39297618/
Keiki Oikawa, Shin-ichiro Ohno, Kana Ono, Kaito Hirao, Ayano Murakami, Yuichirou Harada, Katsuyoshi Kumagai, Katsuko Sudo, Masakatsu Takanashi, Akio Ishikawa, Shouichirou Mineo, Koji Fujita, Tomohiro Umezu, Noriko Watanabe, Yoshiki Murakami, Shinichiro Ogawa, Kris Ann Schultz, and Masahiko Kuroda.
Liver-specific DICER1 syndrome model mice develop cystic liver tumors with defective primary cilia.
J Pathol. 2024 Jun 26. doi: 10.1002/path.6320. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/38922876/
Takakura Y*, Hanayama R* (*co-corresponding authors), Akiyoshi A, Futaki S, Hida K, Ichiki T, Ishii-Watabe A, Kuroda M, Maki M, Miura Y, Okada Y, Seo N, Takeuchi T, Yamaguchi T, Yoshioka Y.
Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles
Pharm Res. 2024 Aug 7. doi: 10.1007/s11095-024-03757-4. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/39112776/
Toru Sasaki, Shinji Suzuki, Masanori Ono, Akiko Yamamoto, Masato Bingo, Gaku Yamanaka, Masahiko Kuroda, Natsuko Inagaki, Hirotaka Nishi.
Case Report: Rare Heterozygous Variant in the NR5A1 Gene Causing 46,XY Complete Gonadal Dysgenesis with a Non-Communicating Rudimentary Uterus
Frontiers in Medicine. 01 August 2024. Volume 11 - 2024 | https://doi.org/10.3389/fmed.2024.1441990
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1441990/full
Tomohiro Umezu, Tomoya Mori, Hidenori Toyoda, Kohsuke Kanekura, Akihiro Tamori, Takahiro Ochiya, Masahiko Kuroda, Tatsuya Akutsu, Yoshiki Murakami.
Analysis of carcinogenic involvement of miRNA pattern in peripheral non-cancerous tissues and chronic viral liver injury
Int J Mol Sci. 2024 Jul 18;25(14):7858. doi: 10.3390/ijms25147858.
https://pubmed.ncbi.nlm.nih.gov/39063098/
Tomofumi Yamamoto, Jun Nakayama, Fumihiko Urabe, Kagenori Ito, Nao Nishida-Aoki, Masami Kitagawa, Akira Yokoi, Masahiko Kuroda, Yutaka Hattori, Yusuke Yamamoto, Takahiro Ochiya.
Aberrant regulation of serine metabolism drives extracellular vesicle release and cancer progression
Cell Rep. 2024 Jul 17;43(8):114517. doi: 10.1016/j.celrep.2024.114517. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/39024098/
Junichi Mazaki, Tomohiro Umezu, Akira Saito, Kenji Katsumata, Koji Fujita, Mikihiro Hashimoto, Masaharu Kobayashi, Ryutaro Udo, Kenta Kasahara, Hiroshi Kuwabara, Tetsuo Ishizaki, Jun Matsubayashi, Toshitaka Nagao, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Takashi Tanaka, Akihiko Tsuchida, Yuichi Nagakawa, Masahiko Kuroda.
Novel AI Combining CNN and SVM to Predict Colorectal Cancer Prognosis and Mutational Signatures from HE Images
Mod Pathol. 2024 Jul 15:100562. doi: 10.1016/j.modpat.2024.100562. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/39019345/
Jeong-Hwan Yoon, Eunjin Bae, Yasuo Nagafuchi, Katsuko Sudo, Jin Soo Han, Seok Park, Susumu Nakae, Tadashi Yamashita, Ji Ju, Isao Matsumoto, Takayuki Sumida, Keiji Miyazawa, Mitsuyasu Kato, Masahiko Kuroda, In-kyu Lee, Keishi Fujio, and Mizuko Mamura.
Repression of SMAD3 by STAT3 and c-Ski induces conventional dendritic cell differentiation.
Life Science Alliance.2024 Jul 3;7(9):e201900581. doi: 10.26508/lsa.201900581. Print 2024 Sep.
https://pubmed.ncbi.nlm.nih.gov/38960622/
Yujin Kudo, Akira Saito, Tomoaki Horiuchi, Kotaro Murakami, Masaharu Kobayashi, Jun Matsubayashi, Toshitaka Nagao, Tatsuo Ohira, Masahiko Kuroda, Norihiko Ikeda.
Preoperative evaluation of visceral pleural invasion in peripheral lung cancer utilizing deep learning technology.
Surg Today. 2024 May 23. doi: 10.1007/s00595-024-02869-z. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/38782767/
Kenta Nagai, Jiro Akimoto, Shinjiro Fukami, Yuki Saito, Emiyu Ogawa, Masakatsu Takanashi, Masahiko Kuroda, Michihiro Kohno.
Efficacy of interstitial photodynamic therapy using talaporfin sodium and a semiconductor laser for a mouse allograft glioma model.
Scientific Reports. 2024 Apr 21;14(1):9137. doi: 10.1038/s41598-024-59955-y.
https://pubmed.ncbi.nlm.nih.gov/38644422/
Kyosuke Matsunaga, Muneaki Kikuno, Hiroki Sakamoto, Hirofumi Okada, Takao Hashimoto, Shogo Honda, Jun Matsubayashi, Toshitaka Nagao, Yuko Yamada, Hajime Horiuchi, Masahiko Kuroda, Shigeo Murayama, Hiroo Terashi, Michihiro Kohno.
A Cerebral Embolism Caused by a Malignant Peripheral Nerve Sheath Tumor in a Patient with Neurofibromatosis Type 1
Intern Med. 2024 Apr 2. doi: 10.2169/internalmedicine.2996-23. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/38569908/

2023 / R5

Natsuko Inagaki, Tomoya Okano, Masatake Kobayashi, Masatsune Fujii, Yoshinao Yazaki, Yasuyoshi Takei, Hisanori Kosuge, Shinji Suzuki, Takeharu Hayashi, Masahiko Kuroda, Kazuhiro Satomi.
Pediatric hypertrophic cardiomyopathy caused by a novel TNNI3 variant.
Hum Genome Var. 2024 Mar 29;11(1):14. doi: 10.1038/s41439-024-00272-1.
https://pubmed.ncbi.nlm.nih.gov/38548731/
Mayu Yoshida, Juntaro Matsuzaki, Koji Fujita, Masamichi Kimura, Tomohiro Umezu, Noi Tokuda, Tomoko Yamaguchi, Masahiko Kuroda, Takahiro Ochiya, Yoshimasa Saito, Kiminori Kimura.
Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis.
Sci Rep 2024 Mar 15;14(1):6266.doi: 10.1038/s41598-024-56942-1.
https://pubmed.ncbi.nlm.nih.gov/38491114/
Joshua A Welsh, Deborah C I Goberdhan, Lorraine O'Driscoll, Edit I Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A P Driedonks, Uta Erdbrügger, Juan M Falcon-Perez, Qing-Ling Fu, Andrew F Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M Bridges, Marco Brucale, Dylan Burger, Randy P Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L Harris, Norman J Haughey, An Hendrix, Alexander R Ivanov, Tijana Jovanovic-Talisman, Nicole A Kruh-Garcia, Vroniqa Ku'ulei-Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M Lennon, Jan Lötvall, Adam L Maddox, Elena S Martens-Uzunova, Rachel R Mizenko, Lauren A Newman, Andrea Ridolfi, Eva Rohde, Tatu Rojalin, Andrew Rowland, Andras Saftics, Ursula S Sandau, Julie A Saugstad, Faezeh Shekari, Simon Swift, Dmitry Ter-Ovanesyan, Juan P Tosar, Zivile Useckaite, Francesco Valle, Zoltan Varga, Edwin van der Pol, Martijn J C van Herwijnen, Marca H M Wauben, Ann M Wehman, Sarah Williams, Andrea Zendrini, Alan J Zimmerman; MISEV Consortium; Clotilde Théry, Kenneth W Witwer.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404.
https://pubmed.ncbi.nlm.nih.gov/38326288/#full-view-affiliation-85
Tomohiro Umezu, Shogo Tanaka, Shoji Kubo, Masaru Enomoto, Akihiro Tamori, Takahiro Ochiya, Y-h Taguchi, Masahiko Kuroda, Yoshiki Murakami.
Characterization of circulating miRNAs in the treatment of primary liver tumors.
Cancer Rep (Hoboken). 2024 Feb;7(2):e1964. doi: 10.1002/cnr2.1964. Epub 2023 Dec 25.
https://pubmed.ncbi.nlm.nih.gov/38146079/
Shigeatsu Takamizawa, Junya Kojima, Tomohiro Umezu, Masahiko Kuroda, Shigehiro Hayashi, Takenori Maruta, Aikou Okamoto, Hirotaka Nishi.
miR‑146a‑5p and miR‑191‑5p as novel diagnostic marker candidates for ovarian clear cell carcinoma.
Mol Clin Oncol. 2023 Dec 28;20(2):14. doi: 10.3892/mco.2023.2712. eCollection 2024 Feb.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10804375/
Kurata A, Harada Y, Fujita K, Ohno SI, Takanashi M, Yoshizawa S, Nagashima Y, Nagao T, Yamaguchi J, Kuroda M.
Smooth muscle differentiation of coronary intima in autopsy tissues after sirolimus-eluting stent implantation.
Cardiovasc Pathol. 2023 Sep-Oct;66:107554. doi: 10.1016/j.carpath.2023.107554. Epub 2023 Jun 13.
https://pubmed.ncbi.nlm.nih.gov/37321466/
Sakiko Naito, Itaru Nakamura, Tomohiro Umezu, Akihiro Hata, Akira Madarame, Kumiko Uchida, Yohei Koyama, Takashi Morise, Hayato Yamaguchi, Shin Kono, Mitsushige Sugimoto, Takashi Kawai, Yuichiro Harada, Masahiko Kuroda, Masakatsu Fukuzawa, Takao Itoi.
Effect of COVID-19 infection on the gastrointestinal tract considering preventive methods during endoscopic procedures
DEN Open. 2023 Aug 27;4(1):e290. doi: 10.1002/deo2.290. eCollection 2024 Apr.
https://pubmed.ncbi.nlm.nih.gov/37644959/#full-view-affiliation-3
Shuya Matsubara, Akira Saito, Naoto Tokuyama, Ryu Muraoka, Takeshi Hashimoto, Naoya Satake, Toshitaka Nagao, Masahiko Kuroda & Yoshio Ohno.
Recurrence prediction in clear cell renal cell carcinoma using machine learning of quantitative nuclear features.
Sci Rep. 2023 Jul 7;13(1):11035. doi: 10.1038/s41598-023-38097-7.
https://www.nature.com/articles/s41598-023-38097-7
Kosuke Oikawa, Masahiko Kuroda and Shogo Ehata.
Suppression of antitumor cytokine IL‑24 by PRG4 andPAI‑1 may promote myxoid liposarcoma cell survival.
Biomedical Reports 19(3): 60, Accepted June 27, 2023. doi: 10.3892/br.2023.1642.
https://www.spandidos-publications.com/10.3892/br.2023.1642
Tamami Miyagi, Koji Ueda, Masahiro Sugimoto, Hiroshi Uji-I, Masahiko Kuroda, Kohsuke Kanekura.
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
iScience. 2023 May 25;26(6):106957. doi: 10.1016/j.isci.2023.106957. eCollection 2023 Jun 16.
https://www.sciencedirect.com/science/article/pii/S2589004223010349
Suguru Saito, Shin-ichiro Ohno, Yuichirou Harada, Yoshihiko Kanno & Masahiko Kuroda.
MiR-34a induces myofibroblast differentiation from renal fibroblasts.
Clinical and Experimental Nephrology (Clin Exp Nephrol) . 2023 May;27(5):411-418. doi: 10.1007/s10157-023-02329-x. Epub 2023 Feb 18.
https://pubmed.ncbi.nlm.nih.gov/36808381/
Bin Shen, Akira Saito, Ai Ueda3 Koji Fujita, Mikihiro Hashimoto, Masaharu Kobayashi, Aashiq H. Mirza, Hans Peter Graf, Eric Cosatto, Shoichi Hazama, Hiroaki Nagano, Toshitaka Nagao, Eiichi Sato, Esther Cheng, Syed AF Hoda, Takashi Ishikawa, Masahiko Kuroda. Development of multiple AI pipeline that predict NAC response of breast cancer using H&E-stained tissues.
J Pathol Clin Res. 2023 May;9(3):182-194. doi: 10.1002/cjp2.314. Epub 2023 Mar 10.
https://pubmed.ncbi.nlm.nih.gov/36896856/
Hiroyuki Komatsu, Yoshihiko Usui, Aoi Sukeda, Yoshinari Yamamoto, Shin-Ichiro Ohno, Keisuke Goto, Masahiko Kuroda, Toshitaka Nagao, Hiroshi Goto.
Prevalence of Merkel Cell Polyomavirus in Primary Eyelid Merkel Cell Carcinomas and Association With Clinicopathological Features.
Am J Ophthalmol. 2023 May;249:49-56. doi: 10.1016/j.ajo.2022.12.001, Epub 2022 Dec 6.
https://pubmed.ncbi.nlm.nih.gov/36493850/

2022 / R4

Hirotaka Nishi, Masanori Ono, Shinichiro Ohno, Zenta Yamanaka, Toru Sasaki, Kazuma Ohyashiki, Junko H Ohyashiki, Masahiko Kuroda.
Hypoxia-induced paclitaxel resistance in cervical cancer modulated by miR-100 targeting of USP15.
Gynecol Oncol Rep. 2023 Jan 21:45:101138. doi: 10.1016/j.gore.2023.101138. eCollection 2023 Feb.
https://pubmed.ncbi.nlm.nih.gov/36714373/
Yasuhiro Katahira, Fumihiro Murakami, Shinya Inoue, Satomi Miyakawa, Eri Sakamoto, Yuma Furusaka, Aruma Watanabe, Ami Sekine, Masahiko Kuroda, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto.
Protective effects of conditioned media of immortalized stem cells from human exfoliated deciduous teeth on pressure ulcer formation.
Front Immunol. 2023 Jan 13;13:1010700. doi: 10.3389/fimmu.2022.1010700. eCollection 2022.
https://www.frontiersin.org/articles/10.3389/fimmu.2022.1010700/full
Erdenetsogt Dungubat, Hiroyuki Kusano, Ichiro Mori, Hirosuke Tawara, Mitsuko Sutoh, Naoki Ohkura, Masakatsu Takanashi, Masahiko Kuroda, Naoki Harada, Emiko Udo, Masakazu Souda, Bungo Furusato, Toshio Fukusato, Yoshihisa Takahashi.
Age-dependent sex difference of non-alcoholic fatty liver disease in TSOD and db/db mice.
PLoS One. 2022 Dec 14;17(12):e0278580. doi: 10.1371/journal.pone.0278580. eCollection 2022.
https://pubmed.ncbi.nlm.nih.gov/36516179/
Kanekura Kohsuke, Yamanaka Yoshiaki; Miyagi Tamami; Kuroda Masahiko.
Chemically oligomerizable TDP-43 a novel chemogenetic tool for studying the pathophysiology of amyotrophic lateral sclerosis.
Neural Regeneration Research: November 2022 - Volume 17 - Issue 11 - p 2434-2436. doi: 10.4103/1673-5374.335803
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120673/
Yoshioka Y, Shimomura M, Saito K, Ishii H, Doki Y, Eguchi H, Nakatsura T, Itoi T, Kuroda M, Mori M, Ochiya T.
Circulating cancer-associated extracellular vesicles as early detection and recurrence biomarkers for pancreatic cancer.
Cancer Sci. 2022 Oct;113(10):3498-3509. doi: 10.1111/cas.15500. Epub 2022 Aug 11.
https://pubmed.ncbi.nlm.nih.gov/35848896/
Kenta Kasahara , Kenji Katsumata, Akira Saito, Tetsuo Ishizaki , Masanobu Enomoto , Junichi Mazaki , Tomoya Tago, Yuichi Nagakawa , Jun Matsubayashi , Toshitaka Nagao , Hiroshi Hirano, Masahiko Kuroda , Akihiko Tsuchida.
Artificial intelligence predicts lymph node metastasis or risk of lymph node metastasis in T1 colorectal cancer.
Int J Clin Oncol 2022 Oct;27(10):1570-1579. doi: 10.1007/s10147-022-02209-6.
https://pubmed.ncbi.nlm.nih.gov/35908272/
Kohsuke Kanekura & Masahiko Kuroda.
How can we interpret the relationship between liquid-liquid phase separation and amyotrophic lateral sclerosis?
Lab Invest. 2022 Sep;102(9):912-918. doi: 10.1038/s41374-022-00791-x. Epub 2023 Jan 4.
https://www.nature.com/articles/s41374-022-00791-x
Tamami Miyagi, Rio Yamazaki, Koji Ueda, Satoshi Narumi, Yuhei Hayamizu, Hiroshi Uji-i, Masahiko Kuroda* and Kohsuke Kanekura.
The Patterning and Proportion of Charged Residues in the Arginine-Rich Mixed-Charge Domain Determine the Membrane-Less Organelle Targeted by the Protein.
Int. J. Mol. Sci. (International Journal of Molecular Sciences) 23(14):7658. 2022 Jul 11 Published. DOI:10.3390/ijms23147658
https://pubmed.ncbi.nlm.nih.gov/35887012/
嶋田善久, 工藤勇人, 牧野洋二郎, 前原幸夫, 萩原優, 垣花昌俊, 大平達夫, 黒田雅彦, 池田徳彦.
呼吸器外科領域におけるAI:現状と未来肺癌手術例におけるシームレスなAIの活用画像診断から病理診断まで
日本呼吸器外科学会雑誌 36(Suppl.) WS1-1 2022年5月.
工藤勇人, 松林純, 梅津知宏, 武内進, 嶋田善久, 牧野洋二郎, 前原幸夫, 萩原優, 垣花昌俊, 大平達夫 ….
肺癌外科におけるゲノム医療肺癌術後再発に対する免疫療法と腫瘍内免疫微小環境.
日本呼吸器外科学会雑誌 36(Suppl.) WS4-1 2022年5月
Tomofumi Yamamoto, Jun Nakayama, Yusuke Yamamoto, Masahiko Kuroda, Yutaka Hattori, Takahiro Ochiya.
SORT1/LAMP2-mediated extracellular vesicle secretion and cell adhesion are linked to lenalidomide resistance in multiple myeloma.
Blood Adv (2022 Apr 26); 6 (8): 2480–2495. doi.org/10.1182/bloodadvances.2021005772
https://pubmed.ncbi.nlm.nih.gov/34979567/
Shin-Ichiro Ohno, Keiki Oikawa, Toshiaki Tsurui, Yuichirou Harada, Kana Ono, Mizumo Tateishi, Aashiq Mirza, Masakatsu Takanashi, Kosuke Kanekura, Kumiko Nagase, Yoshihisa Shimada, Yujin Kudo, Norihiko Ikeda, Takahiro Ochiya, Xiaozhong Wang, Masahiko Kuroda.
Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex.
Cell Reports 2022 Apr 12;39(2):110673. doi: 10.1016/j.celrep.2022.110673.
https://pubmed.ncbi.nlm.nih.gov/35417682/
Saeki C, Matsuzaki J, Kuroda M, Fujita K, Ichikawa M, Takizawa S, Takano K, Oikawa T, Nakanuma Y, Saruta M, Ochiya T, Tsubota A.
Identification of circulating microRNAs as potential biomarkers for hepatic necroinflammation in patients with autoimmune hepatitis.
BMJ Open Gastroenterol. 2022 Apr;9(1):e000879. doi: 10.1136/bmjgast-2022-000879.
https://pubmed.ncbi.nlm.nih.gov/35379653/

2021 / R3

Saeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Masashi Toyoda, Tohru Kimura, Masahiko Kuroda, Atsuko Nakazawa, Mureo Kasahara, Hidenori Nonaka, Akihide Kamiya, Tohru Kiyono, Tohru Kobayshi, Yasufumi Murakami & Akihiro Umezawa.
Drug metabolic activity is a critical cell-intrinsic determinant for selection of hepatocytes during long-term culture
Stem Cell Res Ther. 2022 Mar 12;13(1):104. doi: 10.1186/s13287-022-02776-5.
https://doi.org/10.1186/s13287-022-02776-5
朝蔭正樹, 臼井嘉彦, 禰津直也, 清水広之, 山川直之, 坪田欣也, 高梨正勝, 黒田雅彦, 後藤浩.
サルコイドーシス患者の硝子体液を用いた網羅的miRNA解析による検討.
日本眼科学会雑誌 126(臨増) 209-209 2022年3月
Kohsuke Kanekura, Yuhei Hayamizu, Masahiko Kuroda.
Order controls disordered droplets: structure-function relationships in C9ORF72-derived poly(PR).
Am J Physiol Cell Physiol. 2022 Feb 1;322(2):C197-C204. doi: 10.1152/ajpcell.00372.2021. Epub 2021 Dec 15.
https://pubmed.ncbi.nlm.nih.gov/34910602/
Suzuki Kuno, Igata Hideyoshi, Abe Motoki, Yamamoto Yusuke, Kuroda Masahiko, small RNA based cancer classification project. (164名).
Multiple cancer type classification by small RNA expression profiles with plasma samples from multiple facilities.
Cancer Science. Accepted: 14 February 2022. DOI: 10.1111/cas.15309
https://pubmed.ncbi.nlm.nih.gov/35218669/
Narangerel Jigjidkhorloo, Kohsuke Kanekura, Jun Matsubayashi, Daigo Akahane, Koji Fujita, Keiki Oikawa, Atsushi Kurata, Masakatsu Takanashi, Hitoshi Endou, Toshitaka Nagao, Akihiko Gotoh, Oyundelger Norov & Masahiko Kuroda.
Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin’s lymphoma.
Sci Rep. 2021 Nov 4;11(1):21638. doi: 10.1038/s41598-021-00811-8.
https://www.nature.com/articles/s41598-021-00811-8
Akira Saito, Hidenori Toyoda, Masaharu Kobayashi, Yoshinori Koiwa, Hiroki Fujii, Koji Fujita, Atsuyuki Maeda, Yuji Kaneoka, Shoichi Hazama, Hiroaki Nagano, Aashiq H Mirza, Hans-Peter Graf, Eric Cosatto, Yoshiki Murakami, Masahiko Kuroda.
Prediction of early recurrence of hepatocellular carcinoma after resection using digital pathology images assessed by machine learning
Mod Pathol. 2021 Feb;34(2):417-425. doi: 10.1038/s41379-020-00671-z. Epub 2020 Sep 18.
https://pubmed.ncbi.nlm.nih.gov/32948835/
Tamami Miyagi, Yoshiaki Yamanaka, Yuichiro Harada, Satoshi Narumi, Yuhei Hayamizu, Masahiko Kuroda, Kohsuke Kanekura.
An improved macromolecular crowding sensor CRONOS for detection of crowding changes in membrane-less organelles under stressed conditions
Biochem Biophys Res Commun. 2021 Oct 27;583:29-34. doi: 10.1016/j.bbrc.2021.10.055. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/34717122/
Chen Chen, Yoshiaki Yamanaka, Koji Ueda, Peiying Li, Tamami Miyagi, Yuichiro Harada, Sayaka Tezuka, Satoshi Narumi, Masahiro Sugimoto, Masahiko Kuroda, Yuhei Hayamizu, Kohsuke Kanekura.
Phase Separation and Toxicity of C9orf72 poly(PR) depends on alternate distribution of Arginine.
J Cell Biol. 2021 Nov 1;220(11):e202103160. doi: 10.1083/jcb.202103160. Epub 2021 Sep 9.
https://rupress.org/jcb/article/220/11/e202103160/212626/Phase-separation-and-toxicity-of-C9orf72-poly-PR
Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Tatsunori Nishimura, Minoru Terashima, Yuming Wang, Mengjiao Li, Reiko Sakamoto, Mizuki Yamamoto, Naoki Itano, Yusuke Inoue, Masataka Ito, Nobuaki Yoshida, Jun-Ichiro Inoue, Koichi Akashi, Hideyuki Saya, Koji Fujita, Masahiko Kuroda, Issay Kitabayashi, Dominic Voon, Takeshi Suzuki, Arinobu Tojo, Noriko Gotoh.
The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.
Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2103658118. doi: 10.1073/pnas.2103658118.
https://pubmed.ncbi.nlm.nih.gov/34663724/
Yamada Y, Kurata A, Fujita K, Kuroda M.
Fascin as a useful marker for cancer-associated fibroblasts in invasive lung adenocarcinoma.
Medicine. 2021 Sep 3;100(35):e27162.doi: 10.1097/MD.0000000000027162.
https://pubmed.ncbi.nlm.nih.gov/34477172/
Yoshiaki Yamanaka, Tamami Miyagi, Yuichiro Harada, Masahiko Kuroda, Kohsuke Kanekura.
Establishment of chemically oligomerizable TAR DNA-binding protein-43 which mimics amyotrophic lateral sclerosis pathology in mammalian cells.
Laboratory Investigation. Published: 15 June 2021
https://doi.org/10.1038/s41374-021-00623-4
Kurata A, Takanashi M, Ohno S, Fujita K, Kuroda M.
Cisplatin induces differentiation in teratomas derived from pluripotent stem cells.
Regenerative Therapy 18 (2021) 117-126. Available online 8 June 2021.
https://doi.org/10.1016/j.reth.2021.05.005
Katsuyoshi Kumagai, Masakatsu Takanashi, Shin-ichiro Ohno, Yuichirou Harada, Koji Fujita, Keiki Oikawa, Katsuko Sudo, Shun-ichi Ikeda, Hirotaka Nishi, Kosuke Oikawa & Masahiko Kuroda.
WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7.
Oncogene. 4 May 2021. 40: 3695–3706.
https://www.nature.com/articles/s41388-021-01787-5
Watanabe Noriko; Ohno Shin-ichiro, Sakuma Moe, Kuriwaki Mayo, Miura Mai, Kuroda Masahiko.
A case report on death from acute bacterial cholangitis accompanied by von Meyenburg complexes Use of 16S rRNA gene sequencing to identify pathogenic microbes from postmortem formalin-fixed, paraffin-embedded tissue.
Medicine: April 16, 100(15) - p e25526
doi: 10.1097/MD.0000000000025526
Kana Miyahara, Naoharu Takano, Yumiko Yamada, Hiromi Kazama, Mayumi Tokuhisa, Hirotsugu Hino, Koji Fujita, Edward Barroga, Masaki Hiramoto, Hiroshi Handa, Masahiko Kuroda, Takashi Ishikawa & Keisuke Miyazawa.
BRCA1 degradation in response to mitochondrial damage in breast cancer cells.
Scientific Reports (2021) 11:8735. doi.org/10.1038/s41598-021-87698-7
Tomohiro Umezu, Masakatsu Takanashi, Yoshiki Murakami, Shin Takeuchi, Takahiro Ochiya, Masahiko Kuroda.
Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration.
Mol Ther Metod & Clin Dev. 2021 Mar 10;21:199-208. doi: 10.1016/j.omtm.2021.03.006. eCollection 2021 Jun 11.

2020 / R2

Saito A, Toyoda H, Kobayashi M, Koiwa Y, Fujii H, Fujita K, Maeda A, Kaneoka Y, Hazama S, Nagano H, Mirza AH, Graf HP, Cosatto E, Murakami Y, Kuroda M.
Prediction of early recurrence of hepatocellular carcinoma after resection using digital pathology images assessed by machine learning.
Mod Pathol. 2021
Umezu T, Tsuneyama K, Kanekura K, Hayakawa M, Tanahashi T, Kawano M, Taguchi YH, Toyoda H, Tamori A, Kuroda M, Murakami Y.
Comprehensive analysis of liver and blood miRNA in precancerous conditions.
Sci Rep. 2020 Dec 10;10(1):21766. doi: 10.1038/s41598-020-78500-1. Feb;34(2):417-425. doi: 10.1038/s41379-020-00671-z. Epub 2020 Sep 18.
Naoya Nezu, Yoshihiko Usui, Akira Saito, Hiroyuki Shimizu, Masaki Asakage, Naoyuki Yamakawa, Kinya Tsubota, Yoshihiro Wakabayashi, Akitomo Narimatsu, Kazuhiko Umazume, Katsuhiko Maruyama, Masahiro Sugimoto, Masahiko Kuroda, Hiroshi Goto.
Machine learning approach for intraocular disease prediction based on aqueous humor immune mediator profiles.
Ophthalmology. 2021 Jan 21;S0161-6420(21)00067-1. doi: 10.1016/j.ophtha.2021.01.019. Online ahead of print.
Masako Muguruma, Saeko Teraoka, Kana Miyahara, Ai Ueda, Mariko Asaoka, Miki Okazaki, Takahiko Kawate, Masahiko Kuroda, Yohei Miyagi, Takashi Ishikawa.
Differences in drug sensitivity between two-dimensional and three-dimensional culture systems in triple-negative breast cancer cell lines.
Biochemical and Biophysical Research Communications. 2020 Dec 10;533(3):268-274. doi: 10.1016/j.bbrc.2020.08.075. Epub 2020 Sep 18.
Koichiro Tsujimaru, Masakatsu Takanashi, Katsuko Sudo, Akio Ishikawa, Shoichiro Mineo, Shinobu Ueda, Katsuyoshi Kumagai, Masahiko Kuroda
. Extracellular microvesicles that originated adipose tissue derived mesenchymal stem cells have the potential ability to improve rheumatoid arthritis on mice.
Regen Ther. 2020 Dec 9;15:305-311. doi: 10.1016/j.reth.2020.08.004. eCollection 2020 Dec.
Asakage M, Usui Y, Nezu N, Shimizu H, Tsubota K, Umazume K, Yamakawa N, Umezu T, Suwanai H, Kuroda M, Goto H.
Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing.
J Clin Med. 2020 Oct 27;9(11):3458. doi: 10.3390/jcm9113458.
Masaki Asakage, Yoshihiko Usui, Naoya Nezu, Hiroyuki Shimizu, Kinya Tsubota, Naoyuki Yamakawa, Masakatsu Takanashi, Masahiko Kuroda, Hiroshi Goto.
Comprehensive miRNA Analysis Using Serum from Patients with Noninfectious Uveitis.
Invest Ophthalmol Vis Sci. 2020 Sep 1;61(11):4. doi: 10.1167/iovs.61.11.4.
Izuru Mizoguchi, Mio Ohashi, Hideaki Hasegawa, Yukino Chiba, Naoko Orii, Shinya Inoue, Chiaki Kawana, Mingli Xu, Katsuko Sudo, Koji Fujita, Masahiko Kuroda, Shin-Ichi Hashimoto, Kouji Matsushima, Takayuki Yoshimoto.
EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin.
J Clin Invest. 2020 Aug 18;122732. doi: 10.1172/JCI122732. Online ahead of print.
Naoya Nezu, Yoshihiko Usui, Masaki Asakage, Hiroyuki Shimizu, Kinya Tsubota, Akitomo Narimatsu, Kazuhiko Umazume, Naoyuki Yamakawa, Shin-ichiro Ohno, Masakatsu Takanashi, Masahiko Kuroda and Hiroshi Goto.
Distinctive Tissue and Serum MicroRNA Profile of IgG4-Related Ophthalmic Disease and MALT Lymphoma.
J. Clin. Med. 2020 Aug 5, 9(8), 2530; https://doi.org/10.3390/jcm9082530
Shinobu Ueda, Masakatsu Takanashi, Katsuko Sudo, Kohsuke Kanekura & Masahiko Kuroda.
miR-27a ameliorates chemoresistance of breast cancer cells by disruption of reactive oxygen species homeostasis and impairment of autophagy.
Laboratory Investigation (Lab Invest). vol 100(6), 2020 Jun;100(6):863-873. doi: 10.1038/s41374-020-0409-4. Epub 2020 Feb 17.
Teruumi Minezaki, Yoshihiko Usui, Masaki Asakage, Masakatsu Takanashi, HiroyukiShimizu, Naoya Nezu, Akitomo Narimatsu, Kinya Tsubota, Kazuhiko Umazume, Naoyuki Yamakawa, Masahiko Kuroda and Hiroshi Goto.
High-Throughput MicroRNA Profiling of Vitreoretinal Lymphoma: Vitreous and Serum MicroRNA Profiles Distinct from Uveitis.
J. Clin. Med. 12 June 2020. 9(6), 1844; https://doi.org/10.3390/jcm9061844
Kitamoto K, Taketani Y, Fujii W, Inamochi A, Toyono T, Miyai T, Yamagami S, Kuroda M, Usui T, Ouchi Y.
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Sci Rep. 2020 Feb 6; 10(1):2000. doi: 10.1038/s41598-020-58876-w.

2019 / R1

Akimoto J, Fukami S, Suda T, Ichikawa M, Haraoka R, Kohno M, Shishido-Hara Y, Nagao T, Kuroda M.
First autopsy analysis of the efficacy of intra-operative additional photodynamic therapy for patients with glioblastoma.
Brain Tumor Pathol. 2019 Aug. 36(4):144-151. doi: 10.1007/s10014-019-00351-0. Epub 2019 Sep 5.
Saito S, Ohno S, Harada Y, Oikawa K, Fujita K, Mineo S, Gondo A, Kanno Y, Kuroda M.
rAAV6-mediated miR-29b delivery suppresses renal fibrosis.
Clin Exp Nephrol. 2019 Dec;23(12):1345-1356. doi: 10.1007/s10157-019-01783-w. Epub 2019 Sep 3.
Umehara R, Kurata A, Takanashi M, Hashimoto H, Fujita K, Nagao T, Kuroda M.
Fascin as a useful marker for identifying neural components in immature teratomas of human ovary and those derived from murine embryonic stem cells.
Int J Gynecol Pathol. 2019 Jul;38(4):377-385. doi: 10.1097/PGP.0000000000000528.
Hashimoto H, Horiuchi H, Kurata A, Kikuchi H, Okuyama R, Usui G, Masuda Y, Kuroda M, Inoue S, Furushima K, Matsuhashi N, Harihara Y, Morikawa T.
Intramucosal colorectal carcinoma with lymphovascular invasion: clinicopathological characteristics of nine cases.
Histopathology. 2019 Jun;74(7):1055-1066. doi: 10.1111/his.13826.
Ueda A, Oikawa K, Fujita K, Ishikawa A, Sato E, Ishikawa T, Kuroda M, Kanekura K.
Therapeutic potential of PLK1 inhibition in triple-negative breast cancer.
Lab Invest. 2019 Sep;99(9):1275-1286. doi: 10.1038/s41374-019-0247-4. Epub 2019 Apr 17.
Saito A, Kuroda M.
AI Application on the Pathology-From Diagnosis Assisting Tool to Prediction Tool.
Gan To Kagaku Ryoho. 2019 Mar;46(3):427-431. Japanese.
Kurata A, Saito A, Hashimoto H, Fujita K, Ohno SI, Kamma H, Nagao T, Kobayashi S, Yamashina A, Kuroda M.
Difference in immunohistochemical characteristics between Takayasu arteritis and giant cell arteritis: it may be better to distinguish them in the same age.
Mod Rheumatol. 2019 Nov;29(6):992-1001. doi: 10.1080/14397595.2019.1570999. Epub 2019 Feb 18

2018 / H30

Iida M, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Tokumitsu Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Fujita K, Kuroda M, Nagano H.
Overexpression of miR‑221 and miR‑222 in the cancer stroma is associated with malignant potential in colorectal cancer.br> Oncol Rep. 2018 Sep;40(3):1621-1631. doi: 10.3892/or.2018.6575. Epub 2018 Jul 13.
Higuchi H, Yamakawa N, Imadome KI, Yahata T, Kotaki R, Ogata J, Kakizaki M, Fujita K, Lu J, Yokoyama K, Okuyama K, Sato A, Takamatsu M, Kurosaki N, Alba SM, Azhim A, Horie R, Watanabe T, Kitamura T, Ando K, Kashiwagi T, Matsui T, Okamoto A, Handa H, Kuroda M, Nakamura N, Kotani A.
Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma.
Blood. 2018 Jun 7;131(23):2552-2567. doi: 10.1182/blood-2017-07-794529. Epub 2018 Apr 22.
Ikehata N, Takanashi M, Satomi T, Watanabe M, Hasegawa O, Kono M, Enomoto A, Chikazu D, Kuroda M.
Toll-like receptor 2 activation implicated in oral squamous cell carcinoma development.
Biochem Biophys Res Commun. 2018 Jan 15;495(3):2227-2234. doi: 10.1016/j.bbrc.2017.12.098.
Kurata A, Yamada M, Ohno S, Inoue S, Hashimoto H, Fujita K, Takanashi M, Kuroda M.
Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma.
Oncol Rep. 2018 Jan;39(1):91-100. doi: 10.3892/or.2017.6093.

2017 / H29

Hashimoto H, Kurata A, Kikuchi H, Masuda Y, Fujita K, Okuyama R, Inoue S, Horiuchi H, Kuroda M.
L-type amino acid transporter 1 expression in esophageal carcinogenesis according to WHO and Japanese classifications of intraepithelial neoplasia. Pathol Int. 2017 May;67(5):247-255. doi: 10.1111/pin.12528. Epub 2017 Mar 29.PMID:28370814.
Hongo-Kohama M, Kurata A, Hashimoto H, Fujita K, Horiuchi H, Nagao T, Kuroda M.
Vascular Smooth Muscle Cell Maturation Stage and Ki-67 Index are Diagnostic Biomarkers for Pathologic Grade of Ovarian Teratoma. Int J Gynecol Pathol. 2017 Mar 17. doi: 10.1097/PGP.0000000000000373. [Epub ahead of print] PMID:28319573
ikawa K, Mizusaki A, Takanashi M, Ozaki T, Sato F, Kuroda M, Muragaki Y.
PRG4 expression in myxoid liposarcoma maintains tumor cell growth through suppression of an antitumor cytokine IL-24.Biochem Biophys Res Commun. 2017 Mar 25;485(1):209-214. doi: 10.1016/j.bbrc.2017.02.055. Epub 2017 Feb 10.
Oikawa K, Saito A, Kiyuna T, Graf HP, Cosatto E, Kuroda M.
Pathological Diagnosis of Gastric Cancers with a Novel Computerized Analysis System. J Pathol Inform. 2017 Feb 28;8:5. doi: 10.4103/2153-3539.201114. eCollection 2017.
Makino Y, Yoon JH, Bae E, Kato M, Miyazawa K, Ohira T, Ikeda N, Kuroda M, Mamura M.
Repression of Smad3 by Stat3 and c-Ski/SnoN induces gefitinib resistance in lung adenocarcinoma. Biochem Biophys Res Commun. 2017 Mar 4;484(2):269-277. doi: 10.1016/j.bbrc.2017.01.093. Epub 2017 Jan 20. PMID:28115165.
Yamada Y, Takanashi M, Sudo K, Ueda S, Ohno S, Kuroda M.
Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis. PLoS One. 2017 Feb 24;12(2):e0171957. doi: 10.1371/journal.pone.0171957. eCollection 2017. PMID:28234907.
Kurata A, Nishida J, Koyama T, Miki T, Hashimoto H, Yamamoto K, Kuroda M.
Case report of 2 sudden deaths after surgery for bone fracture:
Usefulness of immunohistochemical analysis of coronary artery for identifying acute myocardial infarction.
Medicine (Baltimore). 2017 May;96(21):e7006. doi: 10.1097/MD.0000000000007006.PMID: 28538416.

2016 / H28

Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, Nishihara H, Yamaguchi H, Hashimoto A, Nishida M, Nagasaka A, Horii Y, Ono H, Iribe G, Inoue R, Tsuda M, Inoue K, Tanaka A, Kuroda M, Nagata S, Kurose H.
Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.
J Clin Invest. 2017 Jan 3;127(1):383-401. doi: 10.1172/JCI83822. Epub 2016 Dec 5.
Matsumoto Y, Itami S, Kuroda M, Yoshizato K, Kawada N, Murakami Y.
MiR-29a Assists in Preventing the Activation of Human Stellate Cells and Promotes Recovery From Liver Fibrosis in Mice.
Mol Ther. 2016 Oct;24(10):1848-1859. doi: 10.1038/mt.2016.127.
Hashimoto H, Hara K, Matsumoto J, Nashiro T, Nagano M, Kusakabe M, Kurata A, Kuroda M, Suzuki Y, Horiuchi H.
Necrotizing arteritis occurring in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome.
Cardiovasc Pathol. 2016 May-Jun;25(3):200-2. doi: 10.1016/j.carpath.2016.01.005. Epub 2016 Jan 22. PMID:26874730.
Ohno S, Itano K, Harada Y, Asada K, Oikawa K, Kashiwazako M, Okuyama H, Kumagai K, Takanashi M, Sudo K, Ikeda N, Kuroda M.
Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2.
Mol Ther. 2016 Aug;24(7):1278-89. doi: 10.1038/mt.2016.81. Epub 2016 Apr 25.
Mori A, Nishi H, Sasaki T, Nagamitsu Y, Kawaguchi R, Okamoto A, Kuroda M, Keiichi Isaka.（Mori A, Nishi H, Sasaki T, Nagamitsu Y, Kawaguchi R, Okamoto A, Kuroda M, Isaka K.）
HLA-G expression is regulated by miR-365 in trophoblasts under hypoxic conditions.
Placenta. 2016 Sep;45:37-41. doi: 10.1016/j.placenta.2016.07.004. Epub 2016 Jul 21.
Fujinaga H, Fujinaga H, Watanabe N, Kato T, Tamano M, Terao M, Takada S, Ito Y, Umezawa A, Kuroda M.
Cord blood-derived endothelial colony-forming cell function is disrupted in congenital diaphragmatic hernia. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1143-54. doi: 10.1152/ajplung.00357.2015. Epub 2016 Apr 29.
Hashimoto H, Kurata A, Fujiwara M, Hara K, Matsumoto J, Kusakabe M, Tachibana K, Nashiro T, Terado Y, Akahane M, Usui K, Suzuki Y, Kondo H, Kamma H, Kuroda M, Horiuchi H.
Solitary Pulmonary Capillary Hemangioma of Adult Cases: Clinicopathologic Characteristics as an Unrecognized Entity.
Am J Surg Pathol. 2016 Oct;40(10):1380-9. doi: 10.1097/PAS.0000000000000708.
Taketani Y, Usui T, Toyono T, Shima N, Yokoo S, Kimakura M, Yamagami S, Ohno S, Onodera R, Tahara K, Takeuchi H, Kuroda M.
Topical Use of Angiopoietin-like Protein 2 RNAi-loaded Lipid Nanoparticles Suppresses Corneal Neovascularization.
Mol Ther Nucleic Acids. 2016 Mar 8;5:e292. doi: 10.1038/mtna.2016.1.
Kanekura K, Nishi H, Isaka K, Kuroda M.
MicroRNA and gynecologic cancers.
J Obstet Gynaecol Res. 2016 Apr 20. doi: 10.1111/jog.12995.
Kanekura K, Yagi T, Cammack AJ, Mahadevan J, Kuroda M, Harms MB, Miller TM, Urano F.
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
Hum Mol Genet. 2016 Feb 29. pii: ddw052.
Ohno S, Drummen GP, Kuroda M.
Focus on Extracellular Vesicles: Development of Extracellular Vesicle-Based Therapeutic Systems.
Int. J. Mol. Sci. 2016 Feb 6;17(2). pii: E172. doi: 10.3390/ijms17020172.
Yamada M, Saito A, Yamamoto Y3 Cosatto E, Kurata A, Nagao T, Tateishi A, Kuroda M.
Quantitative nucleic features are effective for discrimination of intraductal proliferative lesions of the breast.
J Pathol Inform 2016, 7:1 (29 January 2016) DOI: 10.4103/2153-3539.175380

2015 / H27

Hashimoto H, Kurata A, Mizuno H, Nashiro T, Hangaishi A, Kuroda M, Usuki K, Horiuchi H.
Pulmonary arterial hypertension due to pulmonary vascular amyloid deposition in a patient with multiple myeloma.
Int J Clin Exp Pathol. 2015 Nov 1;8(11):15391-5. eCollection 2015. PMID:26823900.
Hashimoto H, Kurata A, Nashiro T, Inoue S, Ushijima T, Fujita K, Kimura T, Kawai K, Horiuchi H, Kuroda M.
Smooth muscle immaturity in the carotid arterial neointima as a prognostic marker for systemic atherogenic cardiovascular events in the Asian male. Int J Clin Exp Pathol. 2015 Nov 1;8(11):14630-9. eCollection 2015. PMID:26823786.
Hashimoto H, Kurata A, Kuroda M, Kishimoto M.
Improvement of IgG4-related Disease with a Supplemental Steroid.
Intern Med. 2015;54(22):2949-50. doi: 10.2169/internalmedicine.54.4561.
Takanashi M, Sudo K, Ueda S, Ohno S, Yamada Y, Osakabe Y, Goto H, Matsunaga Y, Ishikawa A, Usui Y, Kuroda M.
Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model. Mol Ther Nucleic Acids. 2015 Oct 20;4:e258. doi: 10.1038/mtna.2015.34.
Hashimoto H, Kurata A, Nashiro T, Kuroda M, Horiuchi H.
Does perineural invasion of the myenteric plexus have a key role in annular rectal invasion and digestive system symptoms of prostate carcinoma patients?
Med Hypotheses. 2015 Dec;85(6):854-7. doi: 10.1016/j.mehy.2015.09.024. Epub 2015 Sep 28.
Yoon JH, Sudo K, Kuroda M, Taniguchi T, Kato M, Lee IK, Han JS, Nakae S, Imamura T, Kim J, Ju JH, Kim DK, Matsuzaki K, Weinstein M, Nakao A, Matsumoto I, Sumida T, Mamura M.
Phosphorylation status determines the opposing functions of Smad2 and Smad3 as STAT3 cofactors in TH17 differentiation.
Nature communications. 2015 July 21 ;6:7600. doi: 10.1038/ncomms8600.
Nakayama Y, Yamada M, Kurata A, Kiseki H, Kuroda M.
Evaluation of the Human Papillomavirus mRNA Test for the detection of cervical lesions in Japan.
Eur J Gynaec Oncol (European journal of gynaecological oncology). 36(2):192-6. 2015.
Hashimoto H, Kurata A, Fujita K, Shimada H, Nagai T, Horiguchi H, Kuroda M.
Ovarian small cell carcinoma of pulmonary type appearing in ante mortem ascites: An aoutopsy case and review of the literature.
Human Pathology. EHPC-00037; No of Pages 6. 2015 Feb. doi: 10.1016/j.ehpc.2015.02.003.
Nakama T, Yoshida S, Ishikawa K, Kobayashi Y, Zhou Y, Nakao S, Sassa Y, Oshima Y, Takao K, Shimahara A, Yoshikawa K, Hamasaki T, Ohgi T, Hayashi H, Matsuda A, Kudo A, Nozaki M, Ogura Y, Kuroda M, Ishibashi T.
Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin.
Gene Ther. 2015 Feb;22(2):127-37. doi: 10.1038/gt.2014.112. Epub 2014 Dec 11.
Toyono T, Usui T, Yokoo S, Taketani Y, Nakagawa S, Kuroda M, Yamagami S, Amano S.
Angiopoietin-like 7 is an anti-angiogenic protein required to prevent vascularization of the cornea.
PLoS One. 2015 Jan 26;10(1):e0116838. doi: 10.1371/journal.pone.0116838. eCollection 2015.
Horita A, Kurata A, Ohno S, Shimoyamada H, Saito I, Kamma H, Kuroda M.
Immaturity of mooth muscle cells in the neointima is associated with acute coronary syndrome.
Cardiovasc Pathol. 2015 Jan-Feb;24(1):26-32. doi: 10.1016/j.carpath.2014.09.003. Epub 2014 Sep 16.

2014 / H26

Yamada M, Katano H, Yotsumoto M, Hashimoto H, Muramatsu T, Shiotsuka M, Fukutake K, Kuroda M.
Unique expression pattern of viral proteins in human herpesvirus 8-positive plasmablastic lymphoma: a case report.
Int J Clin Exp Pathol. 2014 Aug 15;7(9):6415-8. eCollection 2014.
Tajima K, Miyake T, Koike N, Hattori T, Kumakura S, Yamaguchi T, Matsumoto T, Fujita K, Kuroda M, Ito N, Goto H.
In vivo challenging of polymyxins and levofloxacin eye drop against multidrug-resistant Pseudomonas aeruginosa keratitis.
J Infect Chemother. 2014 Jun;20(6):343-9. doi: 10.1016/j.jiac.2013.10.015. Epub 2013 Dec 11.
Nakaya T, Ogawa S, Manabe I, Tanaka M, Sanada M, Sato T, Taketo MM, Nakao K, Clevers H, Fukayama M, Kuroda M, Nagai R.
KLF5 regulates the integrity and oncogenicity of intestinal stem cells.
Cancer Res. 2014 May 15;74(10):2882-91. doi: 10.1158/0008-5472.CAN-13-2574.
Nakaya T, Morita K, Kurata A, Ushiku T, Igarashi T, Kuroda M, Fukayama M.
Multifocal Kaposiform Hemangioendothelioma in Multiple Visceral Organs: An Autopsy of 9-Day-Old Female Baby.
Human Pathology. 2014 Aug;45(8):1773-7. doi: 10.1016/j.humpath.2014.03.019. Epub 2014 Apr 18.
Nakaya T, Kurata A, Hashimoto H, Nishimata S, Kashiwagi Y, Fujita K, Kawashima H, Kuroda M.
Young-age-onset pancreatoduodenal carcinoma in Shwachman-Diamond syndrome.
Pathol Int. 2014 Feb;64(2):75-80. doi: 10.1111/pin.12133.

2013 / H25

Yoon JH, Jung SM, Park SH, Kato M, Yamashita T, Lee IK, Sudo K, Nakae S, Han JS, Kim OH, Oh BC, Sumida T, Kuroda M, Ju JH, Jung KC, Park SH, Kim DK, Mamura M.
Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.
EMBO Mol Med. 2013 Nov;5(11):1720-39. doi: 10.1002/emmm.201302524. Erratum in: EMBO Mol Med. 2014 May;6(5):703.
Mineo S, Niikura M, Inoue S, Kuroda M, Kobayashi F．
Development of Severe Pathology in Immunized Pregnant Mice Challenged with Lethal Malaria Parasites.
Infection and Immunity. 2013 Oct;81(10):3865-3871. doi: 10.1128/IAI.00749-13.
Nishi H, Kuroda M, Isaka K.
Estrogen and estrogen receptor induce matrix metalloproteinase (MMP)-26 expression in endometrial carcinomacells.
Oncol Rep. 2013 Aug;30(2):751-6. doi: 10.3892/or.2013.2527.
Kurata A, Inoue S, Ohno S, Nakatsubo R, Takahashi K, Ito T, Kawasaki K, Kokubo R, Sakai T, Ubukata J, Matsubara S, Muraoka R, Yamazaki J, Hirose T, Hojo M, Watanabe E, Kuroda M.
Correlation between number of renal cysts and aortic circumferences measured using autopsy material.
Pathol Res Pract. 2013 Jul;209(7):441-7. doi: 10.1016/j.prp.2013.04.012.
Araki-sasaki K, Hirano K, Osakabe Y, Kuroda M, Kitagawa K, Mishima H, Obata H, Yamada M, Maeda N, Nishida K, Kinoshita S.
Classification of secondary corneal amyloidosis and involvement of lactoferrin.
Ophthalmology. 2013 Jun;120(6):1166-72. doi: 10.1016/j.ophtha.2012.11.047.
Araki-Sasaki K, Hirano K, Osakabe Y, Kuroda M, Kitagawa K, Mishima H, Obata H, Yamada M, Maeda N, Nishida K, Kinoshita S.
Classification of secondary corneal amyloidosis and involvement of lactoferrin.
Ophthalmology. 2013 Jun;120(6):1166-72. doi: 10.1016/j.ophtha.2012.11.047.
Mizutani T, Tanaka M, Tanaka R, Takanashi M, Ohno S, Kuroda M.
Correlation analysis between microRNAs and mRNAs regulated by PPARγ in 3T3-L1 adipogenesis.
（脂肪細胞3T3-L1分化のPPARγを中心とした転写ネットワークの解析）
東京医科大学雑誌 71(1) : 19-25, 2013.
Umezu T, Ohyashiki K, Kuroda M, Ohyashiki JH.
Leukemia cell to endothelial cell communication via exosomal miRNAs.
Oncogene. 2013 May 30;32(22):2747-55. doi: 10.1038/onc.2012.295. (IF: 6.373)
Murakami Y, Tamori A, Itami S, Tanahashi T, Toyoda H, Tanaka M, Wu W, Brojigin N, Kaneoka Y, Maeda A, Kumada T, Kawada N, Kubo S, Kuroda M. The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis.
BMC Cancer (Section: Genetics, genomics and epigenetics)　2013 Mar 4;13:99. doi: 10.1186/1471-2407-13-99. (IF:3.33)
Minegishi Y, Shibagaki Y, Mizutani A, Fujita K, Tezuka T, Kinoshita M, Kuroda M, Hattori S, Gotoh N.
An adaptor protein complex of FRS2beta and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation.
Cancer Science. 2013 Mar;104(3):345-52. doi: 10.1111/cas.12086.
Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, Nishihara H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto M, Tsuda M, Kuroda M, Inoue K, Kurose H.
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance.
Nature Communications. 2013Feb 26. 4:1532. doi: 10.1038/ncomms2540. PMCID: PMC3586722.
Katsuda T, Tsuchiya R, Kosaka N, Yoshioka Y, Takagaki K, Oki K, Takeshita F, Sakai Y, Kuroda M, Ochiya T.
Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes.
SCIENTIFIC REPORTS 2013 | 3 : 1197 | DOI: 10.1038/srep01197. 1 February 2013.
Matsubayashi J, Tsuchiya K, Shimizu S, Kitagawa N, Wakabayashi Y, Kuroda M, Sakurai M, Nagao T.
Posterior spinal artery syndrome showing marked swelling of the spinal cord: a clinico-pathological study.
J Spinal Cord Med. 2013 Jan;36(1):31-5. doi: 10.1179/2045772312Y.0000000017.
Ohno S, Takanashi M, Sudo K, Ueda S, Ishikawa A, Matsuyama N, Fujita K, Mizutani T, Ohgi T, Ochiya T, Gotoh N, Kuroda M.
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells.
Molecular Therapy. 21(1):185-191. January 2013. doi: 10.1038/mt.2012.180. (IF:6.873~7.041)
Kurata A, Saji H, Ikeda N, Kuroda M.
Case Report Intracaval and intracardiac extension of invasive thymoma complicated by superior and inferior vena cava syndrome.
Pathology International 2013 Jan;63(1):56-62. doi: 10.1111/pin.12023. (IF:1.722)

2012 / H24

Borjigin N, Ohno S, Wu W, Tanaka M, Suzuki R, Fujita K, Takanashi M, Oikawa K, Goto T, Motoi T, Kosaka T, Yamamoto K, Kuroda M.
TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma.
Biochemical and Biophysical Research Communications 2012 Oct 19;427(2):355-60. doi: 10.1016/j.bbrc.2012.09.063.
Matsunaga Y, Kezuka T, An X, Fujita K, Matsuyama N, Matsuda R, Usui Y, Yamakawa N, Kuroda M, Goto H.
Visual Functional and Histopathological Correlation in Experimental Autoimmune Optic Neuritis.
Invest Ophthalmol Vis Sci. 2012 Oct 9;53(11):6964-71. doi: 10.1167/iovs.12-10559.
Kobayashi S, Yamada-Okabe H, Suzuki M, Natori O, Kato A, Matsubara K, Jau Chen Y, Yamazaki M, Funahashi S, Yoshida K, Hashimoto E, Watanabe Y, Mutoh H, Ashihara M, Kato C, Watanabe T, Yoshikubo T, Tamaoki N, Ochiya T, Kuroda M, Levine AJ, Yamazaki T.
LGR5-positive colon cancer stem cells interconvert with drug-resistant LGR5-negative cells and are capable of tumor reconstitution.
Stem Cells. 2012 Dec;30(12):2631-44. doi: 10.1002/stem.1257. (IF:7.781)
Ohno S, Ishikawa A, Kuroda M.
Roles of exosomes and microvesicles in disease pathogenesis.
Advanced Drug Delivery Reviews. 2013 Mar;65(3):398-401. doi: 10.1016/j.addr.2012.07.019. (IF:11.502)
Hamasaki T, Suzuki H, Shirohzu H, Matsumoto T, D'Alessandro-Gabazza CN, Gil-Bernabe P, Boveda-Ruiz D, Naito M, Kobayashi T, Toda M, Mizutani T, Taguchi O, Morser J, Eguchi Y, Kuroda M, Ochiya T, Hayashi H, Gabazza EC, Ohgi T.
Efficacy of a novel class of RNA interference therapeutic agents.
PLoS One. 2012;7(8):e42655. doi: 10.1371/journal.pone.0042655.
Oikawa K, Tanaka M, Itoh S, Takanashi M, Ozaki T, Muragaki Y, Kuroda M.
A novel oncogenic pathway by TLS-CHOP involving repression of MDA-7/IL-24 expression.
Br J Cancer. 2012 Jun 5;106(12):1976-9. doi: 10.1038/bjc.2012.199. (IF: 5.082)
Yamaguchi G, Takanashi M, Tanaka M, Fujita K, Ohira T, Kuroda M, Ikeda N.
Isolation of miRNAs that target EGFR mRNA in human lung cancer.
Biochem Biophys Res Commun. 420(2):411-6. Apr 6. 2012. doi: 10.1016/j.bbrc.2012.03.008. (IF:2.484)
Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M.
Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen. ]
Cancer Sci. 103(4):821-7. Apr 2012. doi:10.1111/j.1349-7006.2012.02221. x. (IF:3.325)
Malon C, Brachtel E, Cosatto E, Graf HP, Kurata A, Kuroda M, Meyer JS, Saito A, Wu S, Yagi Y.
Mitotic figure recognition: agreement among pathologists and computerized detector. Anal Cell Pathol (Amst).35(2):97-100. Feb 2012. doi:10.3233/ACP-2011-0029. (IF: 0.92)

2011 / H23

Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T.
Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production.
Eur J Immunol. 41(10):2828-39. Oct 2011. doi: 10.1002/eji.201141291. (IF:5.103)
Tsuchida A, Ohno S, Wu W, Borjigin N, Fujita K,Aoki T, Ueda S, Takanashi M, Kuroda M.
miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer.
Cancer science. 2011 Dec;102(12):2264-71. doi: 10.1111/j.1349-7006.2011.02081.x. (IF:3.325)
Onomoto K, Morimoto S, Kawaguchi T, Toyoda H, Tanaka M, Kuroda M, Uno K, Kumada T, Matsuda F, Shimotohno K, Fujita T, Murakami Y.
Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C.
PLoS ONE. 2011;6(5):e19799. doi: 10.1371/journal.pone.0019799. (IF: 4.092)
Suzuki R, Tanaka M, Takanashi M, Hussain A, Yuan B, Toyoda H, Kuroda M.
Anthocyanidins-enriched bilberry extracts inhibit 3T3-L1 adipocyte differentiation via the insulin pathway.
Nutr Metab (Lond). 2011 Mar 8;8:14. doi: 10.1186/1743-7075-8-14. (IF:2.885)
Murakami Y, Toyoda H, Tanaka M, Kuroda M, Harada Y, Matsuda F, Tajima A, Kosaka N, Ochiya T, Shimotohno K.
The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.
PLoS One. 2011 Jan 24;6(1):e16081. doi: 10.1371/journal.pone.0016081. (IF: 4.092)
Ohyashiki K, Umezu T, Yoshizawa S, Ito Y, Ohyashiki M, Kawashima H, Tanaka M, Kuroda M, Ohyashiki JH.
Clinical Impact of Down-regulated Plasma miR-92a Levels in Non-Hodgkin’s Lymphoma.
PLoS ONE. 2011 Feb 24;6(2):e16408 (IF:4.092)

2010 / H22

Ohyashiki JH, Umezu T, Kobayashi C, Hamamura RS, Tanaka M, Kuroda M, Ohyashiki K.
Impact on cell to plasma ratio of miR-92a in patients with acute leukemia: in vivo assessment of cell to plasma ratio of miR-92a.
BMC Res Notes. 2010 Dec 24;3:347.(IF:-)
Murakami Y, Tanaka M, Toyoda H, Hayashi K, Kuroda M, Tajima A and Shimotohno K.
Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C.
BMC Med Genomics. 2010 Oct 22;3:48. (IF:3.693)
Shigoka M, Tsuchida A, Matsudo T, Nagakawa Y, Saito H, Suzuki Y, Aoki T, Murakami Y, Toyoda H, Kumada T, Bartenschlager R, Kato N, Ikeda M, Takashina T, Tanaka M, Suzuki R, Oikawa K, Takanashi M, Kuroda M.
Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development.
Pathol Int.60(5) 351-7 May 2010. (IF:1.624)
Zhang L, Ma J, Takeuchi M, Usui Y, Hattori T, Okunuki Y, Yamakawa N, Kezuka T, Kuroda M, Goto H.
Suppression of Experimental Autoimmune Uveoretinitis by Inducing Differention of Regulatory T Cells via Activation of Aryl Hydrocarbon Receptor.
Investigative Ophthalmology & Visual Science. 51(4):2109-17 Apr 2010. (IF:3.597)
Iejima D, Minegishi Y, Takenaka K, Siswanto A, Watanabe M, Huang L, Watanabe T, Tanaka F, Kuroda M,Gotoh N.
FRS2beta, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding.
Oncogene. 29(21):3087-99. May 27. 2010 (IF:6.373)
Ohtomo T, Miyazawa K, Naito M, Moriya S, Kuroda M, Itoh M, Tomoda A.
Cytoprotective Effect of Imatinib Mesylate in Non-BCR-ABL-expressing Cells and Autophagosome Formation.
Biochem Biophys Res Commun. 391(1):310-5. Jan 1 2010. (IF:2.484)
Murohashi M, Hinohara K, Kuroda M, Isagawa T, Tsuji S, Kobayashi S, Umezawa K, Tojo A, Aburatani H, Gotoh N.
Gene set enrichment analysis provides insight into novel signaling pathways in breast cancer stem cells.
British journal of cancer. 2010 Jan 5;102(1):206-12. (IF:5.042)

2009 / H21

Yamamoto Y, Kosaka N, Tanaka M, Koizumi F, Kanai Y, Mizutani T, Murakami Y, Kuroda M, Miyajima A, Kato T, Ochiya T.
MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma.
Biomarkers. 14(7):529-38 Nov 2009. (IF:2.090)
Higuchi R, Nakamura F, Matsuura Y, Hattori K, Suda H, Kawazaki H, Ohta A, Kuroda M, Matsubayashi J.
Mucinous Carcinoma of the Rectosigmoid Colon, Transforming from a Pedunculated (Ip type) Polypoid Cancer in about One Year, Report of a Case.
Stomach and Intestine(Tokyo). 44(11):1777-84 Oct 2009. (有茎性ﾎﾟﾘｰﾌﾟから発育進展して大腸粘液癌の1例／早期胃癌研究会症例. 胃と腸第44巻第11号別冊)
Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M, Kuroda M.
USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis.
Biochem Biophys Res Commun.16;388(2):366-371 Oct 2009. (IF:2.484)
Takanashi M, Oikawa K, Sudo K, Tanaka M, Fujita K, Kasper R, Matsuzaki M, Kuoda M.
Therapeutic silencing of an endogenous gene by the siRNA cream in an arthritis model mouse.
Gene Therapy, 16(8): 982-989 Aug 2009.(IF:4.538)
Tanaka M, Oikawa K, Takanashi M, Kudo M, Ohyashiki J, Ohyashiki K, Kuroda M.
Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients.
PloS ONE 4 (5): e5532., May 2009. (IF:4.092)
Takanashi M, Oikawa K, Fujita K, Kudo M, Kinoshita M, Kuroda M.
HP1g epigenetically regulates cell differentiation and exhibits potential as a therapeutic target for various types of cancers.
Am J Pathol, 174(1): 309-316, Jan.2009. (IF:4.890)

〜2008 / 〜H20

Matsubayashi J, Takanashi M, Oikawa K, Mingli Xu, Mukai K, Kuroda M, Mukai K.
Expression of G-protein-coupled receptor kinase 4 is associated with breast cancer tumorigenesis.
J Pathol, 216(3): 317–327, Nov 2008. (IF:7.274)
Oikawa K, Akiyoshi A, Tanaka M, Takanashi M, Nishi H, Isaka K, Kiseki H, Idei T, Tsukahara Y, Hashimura N, Mukai K, Kuroda M.
Expression of various types of alternatively spliced WAPL transcripts in human cervical epithelia.
Gene, 423(1):57–62, Oct.2008. (IF:2.266)
Oikawa K, Yoshida K, Takanashi M, Tanabe H, Kiyuna T, Ogura M, Saito A, Umezawa A, Kuroda M.
Dioxin interferes in chromosomal positioning through the aryl hydrocarbon receptor.
Biochem Biophys Res Commun , 374(2):361–364, Sep.2008. (IF:2.484)
Zhang J, Hakansson H, Kuroda M, Yuan L.
Wapl localization on the synaptonemal complex, a meiosis-specific proteinaceous structure that binds homologus chromosomes.
Reprod Domest Anim. 43(1):124-6 Feb 2008 (IF:1.606)
Naoe Y, Setoguchi R, Akiyama K, Muroi S, Kuroda M, Hatam F, Littman DR, Taniuchi I.
Repression of interleukin (IL)-4 in T helper type 1 (Th1) cells by Runx complex through binding to IL-4 silencer.
J Exp. Med., 204(8):1749-1755, Aug.2007 (IF:14.776)
Ohyashiki K, Tauchi T, Kuroda M, Kodama A, Ohyashiki JH.
Recurrent chromosomal aberration at 12q15 in chronic idiopathic myelofibrosis with or without JAK2 V617F multation.
Leukemia, 21(7):1578-80, Jul 2007(IF:8.966)
Ohbayashi T, Oikawa, K, Yamada K, Nishida-Umehara C, Matsuda Y, Satoh H, Mukai H, Mukai K, Kuroda M.
Unscheduled overexpression of human WAPL promotes chromosomal instability.
Biochem Biophys Res Commun. (IF:2.484)356(3):699-704, Mar.2007.
Iwaya K, Oikawa K, Semba S, Tsuchiya B, Mukai Y, Otsubo T, Nagao T, Izumi M, Kuroda M, Domoto H, Mukai K.
Correlation with liver metastasis of the colocalization of Arp2/3 complex and WAVE2 in colorectal carcinoma.
Cancer Sci. 98(7):992-999,Jul.2007
Oikawa K, Ishida T, Imamura T, Yoshida K, Takanashi M, Hattori H, Ishikawa A, Fujita K, Yamamoto K, Matsubayashi J, Kuroda M, Mukai K.
Generation of the novel monoclonal antibody against TLS/EWS-CHOP chimeric oncoproteins that is applicable to one of the most sensitive assays for myxoid and round cell liposarcomas.
Am J Surg Pathol , 30(3):351-6, Mar.2006.
Kuroda M, Oikawa K, Ohbayashi T, Yoshida K, Yamada K, Mimura J, Matsuda Y, Fujii-Kuriyama Y, Mukai K.
A dioxin sensitive gene, mammalian WAPL, is implicated in spermatogenesis.
FEBS Lett, 579(1): 167-172, Jan.2005.
Kuroda M, Kiyono T, Oikawa K, Yoshida K, Mukai K.
The human papillomavirus E6 and E7 inducible oncogene, hWAPL, exhibits potential as a therapeutic target.
Br J Cancer, 92(2): 290-293, Jan.2005.
Oshiro H, Ebihara Y, Serizawa H, Shimizu T, Teshima S, Kuroda M, Kudo M.
Idiopathic retroperitoneal fibrosis associated with immunohematological abnormalities.
Am J Med, 118(7):782-786, Jul.2005.
Kuroda M, Oikawa K, Yoshida K, Takeuchi A, Takeuchi M, Usui M, Umezawa A, Mukai, K.
Effects of 3-Methylcholanthrene on the transcriptional activity and mRNA accumulation of the oncogene hWAPL.
Cancer Lett, 221(1):21-28, Apr.2005.
Kuroda M, Tanabe H, Yoshida K, Oikawa K, Saito A, Kiyuna T, Mizusawa H, Mukai K.
Alteration of chromosome positioning during adipocyte differentiation.
J Cell Sci, 117(pt24): 5897-5903, Nov.2004.
Oikawa K, Ohbayashi T, Kiyono T, Nishi H, Isaka K, Umezawa A, Kuroda M, Mukai K.
Expression of a Novel Human Gene, Human Wings Apart-Like (hWAPL), is associated with cervical carcinogenesis and tumor progression.
Cancer Res, 64(10): 3545-3549, May.2004.
Shinmura K, Ishida T, Goto T, Kuroda M, Hattori H, Nagai S, Imamura T, Mukai K, Imakiire A.
Expression of cyclooxygenase-2 in chondroblastoma: immunohistochemical analysis with special emphasis on local inflammatory reaction.
Virchows Arch, 444(1): 28-35, Jan.2004.
Hattori H, Kuroda M, Ishida T, Shinmura K, Nagai S, Mukai K, Imakiire A.
Human DNA damage checkpoints and their relevance to soft tissue sarcoma.
Pathol Int, 54(1): 26-31, Jan.2004.
Iwaya K, Ogawa H, Kuroda M, Izumi M, Ishida T, Mukai K.
Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis.
Clin Exp Metastasis, 20(6): 525-529, May.2003.
Nakagawa M, Akasaka Y, Kanai T, Yamashita T, Kuroda M, Takayama H, Miyazawa N.
Extragastrointestinal stromal tumor of the greater omentum: Case report and review of the literature.
Hepatogastroenterology, 50(51): 691-695, May.2003.
Oikawa K, Kosugi Y, Ohbayashi T, Kameta A, Isaka K, Takayama M, Kuroda M, Mukai K.
Increased expression of IgE-dependent histamine-releasing factor in endometriotic implants.
J Pathol, 199(3): 318-323, Mar.2003.
Izumi M, Mochizuki M, Kuroda M, Iwaya K, Mukai K.
Angiomyoid proliferative lesion: an unusual stroma-rich variant of Castleman’s disease of hyaline-vascular type.
Virchows Arch, 441: 400-405, 2002.(症例報告)
Ogawa H, Iwaya K, Izumi M, Kuroda M, Serizawa H, Koyanagi Y, Mukai K.
Expression of CD10 by stromal cells during colorectal tumor development.
Hum Pathol, 33 (8): 806-811, Aug 2002.
Domoto H, Hosaka T, Oikawa K, Ohbayashi T, Ishida T, Izumi M, Iwaya K, Toguchida J, Kuroda M, Mukai K.
TLS-CHOP target gene DOL54 expression in liposarcomas and malignant fibrous histiocytomas.
Pathol Int, 52(8): 497-500, Aug.2002.
Iwaya K, Ogawa H, Izumi M, Kuroda M, Mukai, K.
Stromal expression of CD10 in invasive breast carcinoma: a new predictor of clinical outcome.
Virchows Arch, 440(6): 589-593, Jun.2002.
Oikawa K, Ohbayashi T, Mimura J, Fujii-Kuriyama Y, Teshima S, Rokutan K, Mukai K, Kuroda M.
Dioxin stimulates synthesis and secretion of IgE-dependent histamine-releasing factor.
Biochem Biophys Res Commun, 290(3): 984-987, Jan.2002.
高橋　芳久、黒田　雅彦、泉　　美貴、小杉　雅英、塚本理一郎、小林　正之、向井　　清.
下肢を中心に顕著な多発性を示した類上皮血管腫の一例．
病理と臨床、Vol. 20, 1187-1191, 2002.
岩屋　啓一、望月　　衛、泉　　美貴、黒田　雅彦、矢島　澄鎮、向井　　清.
肝囊胞腺腫より発生したと思われる紡錘形細胞肉腫の１例．
診断病理 Vol. 18, 134-136, 2001.
Ohbayashi T, Oikawa K, Iwata R, Kameta A, Evine K, Isobe T, Matsuda Y, Mimura J, Fujii-Kuriyama Y, Kuroda M, Mukai K.
Dioxin induces a novel nuclear factor, DIF-3, that is implicated in spermatogenesis.
FEBS Lett, 508(3): 341-344, Nov 2001.
Oikawa K, Ohbayashi T, Mimura J, Iwata R, Kameta A, Evine K, Iwaya K, Fujii-Kuriyama Y, Kuroda M, Mukai K
Dioxin suppresses the checkpoint protein, MAD2, by an AhR-independent pathway.
Cancer Res, 61(15): 5707-5709, Aug 2001.
Miyazawa K, Iwaya K, Kuroda M, Harada M, Serizawa H, Koyanagi Y, Sato Y, Mizokami Y, Matsuoka T, Mukai K.
Nuclear accumulation of beta-catenin in intestinal-type gastric carcinoma: Correlation with early tumor invasion.
Virchows Arch, 437, 508-513, 2000.
Kani Y, Iwaya K, Kuroda M, Harada M, Hirata F, Mukai K.
A case of cytophagic histiocytic panniculitis associated with exertional rhabdomyolysis.
Pathol Int, 50, 858-862, 2000.
Kuroda M, Sok J, Webb L, Baechtold H, Urano F, Yin Y, Chung P, de Rooij DG, Akhmedov A, Ashley T, Ron D.
Male sterility and enhanced radiation sensitivity in TLS-/- mice.
EMBO J, 19(3): 453-462, Feb 1, 2000.
Baechtold H, Kuroda M, Sok J, Ron D, Lopez BS, Akhmedov AT.
Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation.
J Biol Chem, 274(48): 34337-34342, Nov 1999.
Kuroda M, Wang X, Sok J, Yin Y, Chung P, Giannotti JW, Jacobs KA, Fitz LJ, Murtha-Riel P, Turner KJ, Ron D.
Induction of a secreted protein by the myxoid liposarcoma oncogene.
Proc Natl Acad Sci USA, 96(9): 5025-5030, Apr 1999.
Kashima T, Kawaguchi J, Takeshita S, Kuroda M, Takanashi M, Horiuchi H, Imamura T, Ishikawa Y, Ishida T, Mori S, Machinami R, Kudo A.
Anomalous cadherin expression in osteosarcoma: Possible relationships to metastasis and morphogenesis.
Am J Pathol, 155(5): 1549-1555, Nov 1999.
Sok J, Wang XZ, Batchvarova N, Kuroda M, Harding H, Ron D.
CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI.
Mol Cell Biol, 19(1): 495-504, Jan 1999.
Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D.
Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
EMBO J, 17(19): 5708-5717, Oct 1998.
Wang XZ, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, Zinszner H, Ron D.
Identification of novel stress-induced genes downstream of chop.
EMBO J, 17(13): 3619-3630, Jul 1998.
Zou YR, Kottmann AH, Kuroda M, Taniuchi I and Littmann DR: Function of the Chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature, 393(6685): 595-599, Jun 1998.
Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D.
CHOP is implicated in programmed cell death in response to impaired function of the Endoplasmic Reticulum.
Genes & Dev, 12(7): 982-995, Apr 1998.
Motoi T, Ishida T, Kuroda M, Horiuchi H, Oka T, Matsumoto K, Nakamura T, Machinami R.
Coexpression of hepatocyte growth factor and c-Met protooncogene product in synovial sarcoma.
Pathol Int, 48: 769-775, 1998.
Ishida T, Kuroda M, Motoi T, Oka T, Imamura T, Machinami R.
Phenotypic diversity of neurofibromatosis 2: association with plexiform schwannoma.
Histopathology, 32(3): 264-270, 1998.
Miura T, Miyazaki T, Kuroda M, Oka T, Machinami R, Kodama T, Shibuya M, Makuuchi M, Yazaki Y, Ohnishi S
Increased expression of vascular endothelial growth Factor in human hepatocellular carcinoma.
J Hepatol, 27(5): 854-861, 1997.
Kashima, T, Matsushita, H, Kuroda, M, Takeuchi, H, Udagawa, H, Ishida, T, Hara, M, Machinami, R.
Biphasic synovial sarcoma of the peritoneal cavity with t(X;18) demonstrated by Reverse transcriptase polymerase chain reaction.
Pathol Int, 47: 637-641, 1997.
Kuroda M, Ishida T, Takanashi M, Satoh M, Machinami R, Watanabe T.
Oncogenic transformation and inhibition of adipocytic conversion of preadipocyte by TLS/FUS-CHOP typeII chimeric protein.
Am J Pathol, 151(3): 735-744, Sep 1997.
Satoh M, Nara T, Janecharut T, Furta T, Kikuchi T, Matsumoto N, Kokaze A, Kuramochi T, Kuroda M, Hattori S, Ono F, Morishita Y, Mori S, Kojima S.
Squirrel monkeys as a useful vaccine model for Schistosoma japonicum infection.
Parastiology Int, 46: 31-39, 1997.
Kuroda M, Ishida T, Horiuchi H, Kida N, Uozaki H, Takeuchi H, Tsuji K, Imamura T, Mori S, Machinami R, Watanabe T.
Chimeric TLS/FUS-CHOP gene expression and the heterogeneity of its junction in human myxoid and round cell liposarcoma.
Am J Pathol, 147(5): 1221-1227, Nov 1995.
Kuroda M, Oka T, Oka Y, Yamochi T, Ohtsubo K, Mori S, Watanabe T, Machinami R, Ohnishi S.
Colocalization of vascular endothelial growth factor(Vascular permeability factor) and insulin in Pancreatic islet cells.
J Clin Endocrinol Metab, 80(11): 3196-3200, Nov 1995.
Matsushita H, Hara M, Honda K, Kuroda M, Usui M, Nakazawa H, Hara S, Shishiba Y.
Inhibition of parathyroid hormone-related protein release by extracellular calcium in dispersed cells from human parathyroid hyperplasia secondary to chronic renal failure and adenoma.
Am J Pathol, 146(6): 1521-1528, Jul 1995.
岡　　輝明、森　　正也、黒田　雅彦、宇於崎　宏、町並　陸生、四元　秀毅.
肺癌組織におけるcytokeratin 19 fragment (CYFRA21-1)の免疫組織学的検討.
腫瘍マーカー研究会誌, 10:p75-77, 1995
Kuroda M, Oka T, Horiuchi H, Ishida T, Machinami R, Hebisawa A.
Giant cell tumor of the lung:an autopsy case report with immunohistochemical observations.
Pathol Int, 44: 158-163, 1994.
Ishida T, Kojima T, Iijima T, Oka T, Kuroda M, Horiuchi H, Imamura T, Machinami R.
Synovial sarcoma with a predominant epithelial component.
Int J Surg Pathol, 1: 261-268, 1994.
Kuroda M, Horiuchi H, Oka T, Ishida T, Ono A, Kawakita M, Machinami R.
Calcium pump expression in human bone and soft tissue tumors.
Virchows Arch A Pathol Anat Histopathol, 423(3): 209-213, Jul 1993.
Kuroda M, Horiuchi H, Ono A, Kawakita M, Oka T, Machinami R.
Immunohistochemical study on the distribution of sarcoplasmic reticulum calcium ATPase in various human tissues using novel monoclonal antibodies.
Virchows Arch A Pathol Anat Histopathol, 421(6): 527-532, Aug 1992.