2016年3月

医学博士

日本免疫学会
The Korean Association of Immunobiologists、Korean Society for Molecular and Cellular Biology

• The 44th Annual Meeting of The Japanese Society for Immunology, STAT3-induced Downregulation of Smad3 Selects Smad2 for TGF-β to Suppress the Immunogenicity of Dendritic Cells. 11. 20, 2015.
• The 43rd Annual Meeting of the Japanese Society for Immunology, Kyoto, Japan, Linker-phosphorylated Smad2 and C-terminally unphosphorylated Smad3 oppositely regulate Th17 differentiation as transcriptional cofactors of STAT3. 12. 12, 2014.
• Seminar of Department molecular pathology, Tokyo Medical University, Tokyo, Japan, Linker-phosphorylated Smad2 and C-terminally Unphosphorylated Smad3 Oppositely Regulate Th17 differentiation as Transcriptional Cofactors of STAT3. 4. 7, 2014.
• Self-Damage Defense Immune-Network Convergence Research Workshop, Dong-A University, Busan, Korea, Distinct roles of T cell-intrinsic Smad4 in the pathogenesis of contact hypersensitivity. 2. 27, 2014.
• 15th International congress of Immunology, Milan, Italy, Phosphorylation status determines the divergent roles of Smad2 and Smad3 as STAT3 cofactors in Th17 differentiation. 8. 27, 2013.
• 2011 The Annual Meeting of the Japanese Society for Immunology, Chiba, Japan, CD8+ T cell-intrinsic Smad4 suppresses Th2 response in DNFB-induced contact hypersensitivity. 11. 27, 2011.

(First author / Last author）

• Yoon JH, Sudo K, Han JS, Chae MY, Park SH, Weinstein M, Nakae S, Yamashita T, Lee IK, Sumida T, Kuroda M, Mamura M.
  Smad2 is the TGF-receptor-regulated Smad to suppress the immunogenicity of mouse and human dendritic cells.
  American Association for Cancer Research Annual Meeting 2013, Washington DC, USA, 4.7,2017.
• Opposing roles of Smad2 and Smad3 as transcription cofactors of STAT3 in Th17 differentiation.
  The 59th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, Nagoya, Japan. 4. 23, 2015.
• KSBMB International Conference 2015, Seoul, Korea, Opposing roles of Smad2 and Smad3 as transcription cofactors of STAT3 in Th17 differentiation. 5. 13, 2015.
• Yoon JH, Sudo K, Kuroda M, Lee IK, HAN JS, Nakae S, Kim J, Ju JH, Matsumoto I, Sumida T, Mamura M.
  Linker-phosphorylated Smad2 and C-terminally unphosphorylated Smad3 oppositely regulate Th17 differentiation as transcriptional cofactors of STAT3.
  The 43rd Annual Meeting of the Japanese Society for Immunology, Kyoto, Japan, 12. 12, 2014.
• Yoon JH, Sudo K, Han JS, Chae MY, Park SH, Weinstein M, Nakae S, Yamashita T, Lee IK, Sumida T, Kuroda M, Mamura M.
  Smad2 is the TGF-receptor-regulated Smad to suppress the immunogenicity of mouse and human dendritic cells.
  The Joint international Meeting of The 78th Meeting of the Japanese Society of interferon and Cytokine Research, The 21st International Symposium on Molecular Cell Biology of Macrophage 2013 – Cross-talk between innate and adaptive immunity: network among macrophage, dendritic cells and helper T cells, Tokyo, Japan. 5. 20, 2013.
• Yoon JH, Sudo K, Han JS, Weinstein M, Nakae S, Lee IK, Sumida T, Kuroda M, Mamura M.
  CD8+ T Cell-intrinsic Smad4 Suppresses Eomesodermin and Th2 Response In DNFB-induced Contact Hypersensitivity.
  The 25th Annual meeting of Japanese Society of Allegology, Yokohama, Japan. 5. 11, 2013.
• Shin JW, Yoon JH, Park HY, Kang YJ, Lee HJ, Chae MY, Park SH, Weinstein M, Nakae S, Yamashita T, Sudo K, Masahiko Kuroda M, Mamura M.
  Smad2 is a predominant TGF-β receptor-regulated Smad to suppress the immunogenic function of mouse and human myeloid dendritic cells.
  The 12th International Symposium on Dendritic Cells-New Paradigm of DC Science and Application, Daegu, Korea. 10. 7-11, 2012.
• Yoon JH, Lee HJ, Kang YJ, Sudo K, Nakae S, Masumoto I, Sumida T, Kim OH, Oh BC, Kuroda M, Mamura M.
  CD8+ T cell-intrinsic Smad4 suppresses Th2 response in DNFB-induced contact hypersensitivity.
  2011 The Annual Meeting of the Japanese Society for Immunology, Chiba, Japan. 11. 27, 2011.
• Yoon JH, Lee HJ, Kang YJ, Park HY, Park JA, Im KI, Kim JS, Mamura M.
  CD8+ T Cell-intrinsic Smad4 Suppresses Eomesodermin and Th2 Response in DNFB-induced Contact Hypersensitivity.
  Keystone Symposium, TGF-beta in Immune Responses: From Bench to Bedside (A2), Snowbird, Utah, USA. 1.7-12,2011.
• Mamura M, Lee HJ, Kang YJ, Park HY, Deng C, Sudo K, Nakae S, Matsumoto I, Sumida T, Kim OH, Oh BC, Yoon JH.
  TGF-β signaling through Smad3 and Smad4 targets Eomesodermin to suppress CD8+ cytotoxic T cells in DNFB-induced contact hypersensitivity.
  The 22nd Annual Meeting of the Korean Society for Molecular and Cellular Biology, Seoul, Korea. 10.7-8, 2010.
• Yoon JH, Lee HJ, Kang YJ, Park HY, Deng C, Sudo K, Nakae S, Matsumoto I, Sumida T, Kim OH, Oh BC, Mamura M.
  TGF-β signaling through Smad4 suppresses CD8+ cytotoxic T cells by down-regulating Eomesodermin in contact hypersensitivity.
  14th International Congress of Immunology, Kobe, Hyogo, Japan. 8.22-8.27, 2010.
• Yoon JH, Lee HJ, Kang YJ, Park HY, Park JA, Kim JS, Deng C, Sudo K, Nakae S, Matsumoto I, Sumida T, Kim OH, Oh BC, Mamura M.
  TGF-β signaling through Smad3 and Smad4 targets Eomesodermin to suppress CD8+ cytotoxic T cells in DNFB-induced contact hypersensitivity.
  The 59th Fujihara International Seminar “Molecular mechanisms of TGF-β signaling and disease” organized by Prof. Kohei Miyazono, Tomakomai, Hokkaido, Japan. 7.14-7.17, 2010.

• Lee HJ ,Yoon JH ,Shin JW, Kang YJ, Park HY, Sudo K, Nakae S, Matsumoto I, Takayuki S, Yamashita T, Joo JH, OH BC, Mamura M.
  Divergent roles of Smad2 and Smad3 as transcription cofactors of STAT3 in Th17 differentiation.
  2011 The Annual Meeting of the Japanese Society for Immunology, Chiba, Japan. 11.27, 2011.
• Lee HJ, Yoon JH, Kang YJ, Park HY, Mamura M.
  Divergent Roles of Smad2 and Smad3 in Stat3 Activation in Arthritogenic T Helper 17 Cells.
  Keystone Symposium, TGF-beta in Immune Responses: From Bench to Bedside (A2), Snowbird, Utah, USA. 1.7-12, 2011.
• Kang YJ, Lee HJ, Yoon JH, Park HY, Mamura M.
  Distinct Roles of T cell intrinsic Smad2 in the regulation of primary tumor and metastasis.
  Keystone Symposium, TGF-beta in Immune Responses: From Bench to Bedside (A2), Snowbird, Utah, USA. 1.7-12, 2011.
• Park HY, Kang YJ, Lee HJ, Yoon JH, Mamura M.
  Differential roles of Smad2 and Smad3 in development, differentiation, maturation and function of murine bone marrow derived dendritic cells.
  Keystone Symposium, TGF-beta in Immune Responses: From Bench to Bedside (A2), Snowbird, Utah, USA. 1.7-12, 2011.
• Mamura M, Kang YJ, Lee HJ, Yoon JH, Chae MY, Festing MH, Weinstein M, Deng C, Park SH, Sudo K, Park HY.
  Differential roles of Smad2 and Smad3 in differentiation, maturation and development of murine bone marrow derived myeloid dendritic cells.
  The 22nd Annual Meeting of the Korean Society for Molecular and Cellular Biology, Seoul, Korea. 10.7-8, 2010.
• Mamura M, Yoon JH, Kang YJ, Park HY, Festing MH, Michael Weinstein M, Deng C, Sudo K, Nakae S, Matsumoto I, Sumida T, Kim OH, Oh BC, Lee HJ.
  Divergent roles of Smad2 and Smad3 in the regulation of arthritogenic T helper 17 cells.
  The 22nd Annual Meeting of the Korean Society for Molecular and Cellular Biology, Seoul, Korea. 10.7-8, 2010.
• Park HY, Kang YJ, Lee HJ, Yoon JH, Chae MY, Festing MH, Weinstein M, Deng C, Park SH, Sudo K, Mamura M.
  Differential roles of Smad2 and Smad3 in development, maturation and function of murine bone marrow derived dendritic cells.
  DC2010: Forum on Vaccine Science, 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology, Lugano, Switzerland. 9.26-30, 2010.
• Park HY, Kang YJ, Lee HJ, Yoon JH, Chae MY, Festing MH, Weinstein M, Deng C, Park SH, Sudo K, Mamura M.
  Differential roles of Smad2 and Smad3 in differentiation, maturation and development of murine bone marrow derived myeloid dendritic cells.
  14th International Congress of Immunology, Kobe, Hyogo, Japan. 8.22-8.27, 2010.
• Lee HJ, Yoon JH, Kang YJ, Park HY, Festing MH, Weinstein M, Deng C, Sudo K, Nakae S, Matsumoto I, Sumida T, Kim OH, Oh BC, Mamura M. Opposing role of Smad2 and Smad3 in Th17 differentiation in the pathogenesis of collagen-induced arthritis.
  14th International Congress of Immunology, Kobe, Hyogo, Japan. 8.22-8.27, 2010.
• Lee HJ, Yoon JH, Kang YJ, Park HY, Festing MH, Weinstein M, Deng C, Sudo K, Nakae S, Ito S, Tsutsumi A, Matsumoto I, Sumida T, Cha JY, Kim OH, Oh BC, Mamura M.
  Divergent Roles of Smad2 and Smad3 in the Regulation of Arthritogenic T Helper 17 Cells.
  The 59th Fujihara International Seminar “Molecular mechanisms of TGF-β signaling and disease” organized by Prof. Kohei Miyazono, Tomakomai, Hokkaido, Japan. 7.14-7.17, 2010.

• Yoon JH, Sudo K, Kuroda M, Kato M, Lee IK, Han JS, Nakae S, Imamura T, Kim JR, Ju JH, Kim DK, Matsuzaki K, Weinstein M, Matsumoto I, Sumida T, Mamura M.
  Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation.
  Nature Commun. doi:10.1038/ncomms8600, 2015, IF: 11.47.
• Yoon JH, Jung SM, Park SH, Kato M, Yamashita T, Lee IK, Sudo K, Nakae S, Han JS, Kim OH, Oh BC, Sumida T, Kuroda M, Ju JH, Jung KC, Park SH, Kim DK, Mamura M.
  Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.
  EMBO Mol Med. 11:1720-1739, 2013, IF: 8.665.
• Kim OH, Kang GH, Noh H, Cha JY, Lee HJ, Yoon JH, Mamura M, Nam JS, Lee DH, Kim YA, Park YJ, Kim H, Oh BC.
  Proangiogenic TIE2(+)/CD31 (+) macrophages are the predominant population of tumor-associated macrophages infiltrating metastatic lymph nodes.
  Mol Cells. 36:432-438, 2013, IF: 2.090.
• Yoon JH, Kang YJ, Shin JW, Oh IH, Lee SP, Kim SY, Park SH, Mamura M.
  Inhibition of erythropoiesis by Smad6 in human cord blood hematopoietic stem cells.
  Biochem Biophys Res Commun. 13;423:750-756, 2012, * Equal contribution, IF: 2.297 Highlighted by Hematopoiesis News 3.24.
  (http://connexoncreative.com/publications/archives/HN324.aspx)